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Models for the Transmission Dynamics of Gonorrhea in a Homosexually-Active Population

The purpose of this project is to study two questions associated with the transmission dynamics of gonorrhea in a homosexually-active population. First, we examine the impact of a partially effective vaccine on gonorrhea dynamics. Second, we analyze the role of an antibiotic-driven mutation with respect to the survival and spread of resistant gonorrhea strains. Third, we study a model that combines the factors -vaccination and multiple strains of gonorrhea-considered in the first two models. We also explore the influence of heterogeneity and age-structure. Finally, we give a partial mathematical analysis of the system, including the computation of its basic reproduction number.

Article Number:
BU-1426-M

Year:
1997

Authors:
Sharon K. Lima, Purdue University
Mabel Torres, University of Miami

models_for_the_transmission_dynamics_of_gonorrhea_in_a_homosexually-active_population_.pdf